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In 2006, 454 collaborated with Swedish paleogeneticist Svante Pääbo to sequence the first million base pairs of the Neanderthal genome; the project would be completed four years later, albeit with some help from Illumina sequencing. Illumina and other subsequent NGS technologies rendered pyrosequencing non-competitive, and in 2013, 454 was shut down by Roche, which had acquired it six years earlier. The technology is still used today for some applications, but most importantly, it was the first commercially viable alternative to Sanger sequencing, and the first sequencing method that could be fully automated because it didn’t rely on gels or other tedious steps.。关于这个话题,51吃瓜提供了深入分析
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在我们评测华为「二合一」产品 MatePad Edge 时,编辑部那些伴随着平板长大的年轻同事,虽然 80% 的工作时间都在用键鼠,但也会自然地经常伸手点击屏幕,甚至换回 MacBook 后还有点不太习惯。
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